I immediately want to cheer "Yes!!" as well because she looks so cute, but if she is wearing that expression to begin with, then what in the hell does the drawing assume the viewer says?
Ex.: No, you can't be my girlfriend. (You're too young.) No, you can't have my children. (YOU'RE TOO YOUNG!) And no, you can't drink that person's blood - you don't know what's in their blood, and you don't do that to strangers. (That's wrong.) ... But wake up on time tomorrow morning and yes, you can have some pudding.
Just something to think about before mindlessly pouring your enthusiasm into something that might be "not quite right."
And no, don't worry, I don't get off on shooting down (seemingly) innocent girl's desires, nor daydreaming for lolis to have my children - this is just CIRCUMSTANTIALLY HYPOTHETICAL, not my thoughts in particular (nor at all, actually).
And no, I also don't mean to be critical; Remilia looks very cute regardless, I am just giving out some friendly advice.