Basically a parody of those passive-aggressive images like "Other Girls vs Me" or "Gamer Chick vs Girls Who Play Video Games" along the same lines of the "Virgin vs Chad" meme, with additional art amended / added on to the bottom to show the two subjects accepting each other's differences and falling in love.
It's a sort of anit-gatekeeping, pro-LGBTQ, snark meme that became an excuse for artists to draw cute yuri couples of clashing subject matter.
The twitter source has the comic that this piece might have been based off of somewhere in its comments section.
Basically a parody of those passive-aggressive images like "Other Girls vs Me" or "Gamer Chick vs Girls Who Play Video Games" along the same lines of the "Virgin vs Chad" meme, with additional art amended / added on to the bottom to show the two subjects accepting each other's differences and falling in love.
It's a sort of anit-gatekeeping, pro-LGBTQ, snark meme that became an excuse for artists to draw cute yuri couples of clashing subject matter.
The twitter source has the comic that this piece might have been based off of somewhere in its comments section.
It appears to be based on this comic, called "De-Bimbofication", from February 2017.