He and his younger brother Kaiba Mokuba were adopted from an orphanage by Gozaburo Kaiba. Arrogant and power-driven, he believes that he is the best duelist in the world. Seto took over his stepfather's company Kaiba Corporation at a young age and became the president of Kaiba Corp, turning it from a major arms dealer to the biggest gaming company in the world of Yu-Gi-Oh! and among the most influential in the United States.
His signature monster is the Blue-Eyes White Dragon. A monster that he is so highly obsessed about it that he included its motif on almost anything he have.